[BOOK|EPUB] Antibacterial Chemotherapeutic Agents

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Fig 3 Antibiotics that act at the level of protein synthesis initiation Fig 4 Antibiotics that act at the level of the elongation phase of protein synthesis Streptomycin Neomycin Tetracycline Spectinolycin Tetracyclines bacteriostatic Tetracycline, minocycline and doxycycline a. Host defenses are relatively ineffective at these sites and the dangers imposed by such infections require prompt eradication of the organisms.

Resistance that appears after introduction of an antimicrobial agent into the environment usually results from a selective process, i. Yeasts were totally killed in 1 h by garlic extract but in 5 h with clove. Figure 5 summarizes the pathway of folic acid metabolism and indicates the sites at which antimetabolites act.

Antibacterial Chemotherapeutic Agents - In general the use of bactericidal antibiotics is preferred but many factors may dictate the use of a bacteriostatic antibiotic. This combination blocks two distinct steps in folic acid metabolism and prevents the emergence of resistant strains.